Synthesis of the ABH rings of ecteinascidin 597 using a connective Pummerer-type cyclisation.

نویسندگان

  • Laura H S Smith
  • Trung Thanh Nguyen
  • Helen F Sneddon
  • David J Procter
چکیده

A connective Pummerer-type cyclisation involving a cysteine derivative and an N-benzyl glyoxamide 3 has been applied in an asymmetric synthesis of the protected ABH rings 2 of the antitumour and antimicrobial natural product ecteinascidin 597.

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عنوان ژورنال:
  • Chemical communications

دوره 47 38  شماره 

صفحات  -

تاریخ انتشار 2011